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Microcystic Cyanobacteria Extract Induces Cytoskeletal Disruption and Intracellular Glutathione Alteration in Hepatocytes

By Ding, Wen-Xing

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Book Id: WPLBN0000018543
Format Type: PDF eBook
File Size: 0.4 MB
Reproduction Date: 2005
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Title: Microcystic Cyanobacteria Extract Induces Cytoskeletal Disruption and Intracellular Glutathione Alteration in Hepatocytes  
Author: Ding, Wen-Xing
Volume:
Language: English
Subject: Government publications, United Nations., United Nations. Office for Disarmament Affairs
Collections: Government Library Collection, Disarmament Documents
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Publisher: United Nations- Office for Disarmament Affairs (Unoda)

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Ding, W. X. (n.d.). Microcystic Cyanobacteria Extract Induces Cytoskeletal Disruption and Intracellular Glutathione Alteration in Hepatocytes. Retrieved from http://hawaiilibrary.net/


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Government Reference Publication

Excerpt
Excerpt: The occurrence of heavy freshwater blooms of cyanobacteria (blue-green algae) has been well reported in many parts of the world (1). Among the toxic blue-green algae, Microcystis is the most common genera producing microcystins, a group of toxins with strong hepatotoxicity (1,2). These toxins are able to cause the death of domestic and wild animals as well as human illness (3). Recently, it has been reported that dialysis patients in Brazil died of acute hepatic failure due to cyanobacteria contamination of the water used for dialysis (4,5). Recent epidemiologic studies have suggested that the cyanobacteria-contaminated water could be related to the high incidence of primary liver cancer in certain areas of China (6,7). Our previous study also showed that microcystic cyanobacteria extract (MCE) of a water source in China had potent genotoxicity (8).

 

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