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Bulletin of the World Health Organization : 1972; Volume 47; Volume 47, Number 2, Year 1972 47 (2), Pages 195-210: An Attempt to Culture Mycobacterium Leprae in Cell-Free, Semisynthetic, Soft Agar Media

By Toyoho Murohashi

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Book Id: WPLBN0000025017
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Reproduction Date: 2005

Title: Bulletin of the World Health Organization : 1972; Volume 47; Volume 47, Number 2, Year 1972 47 (2), Pages 195-210: An Attempt to Culture Mycobacterium Leprae in Cell-Free, Semisynthetic, Soft Agar Media  
Author: Toyoho Murohashi
Volume:
Language: English
Subject: Health., Public health, Wellness programs
Collections: Medical Library Collection, World Health Collection
Historic
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Publisher: World Health Organization

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Murohashi, T. (n.d.). Bulletin of the World Health Organization : 1972; Volume 47; Volume 47, Number 2, Year 1972 47 (2), Pages 195-210. Retrieved from http://hawaiilibrary.net/


Description
Medical Reference Publication

Excerpt
It has been known since 1957 that Mycobacterium leprae will grow in the foot-pads of mice, hut the conditions required for consistent results, particularly the relationship between time and the number of bacilli, were not clear until 1960 (Shepard, 1960a, 1960h). The observations have subsequently been confirmed in many lahorator~es (Rees, 1964; Pattyn & Janssens, 1965; Maeda & Nakamura, 1968; Levy, Murray & Sbepard, 1970; etc.). Transmission has also been achieved in several other species of small rodent n hitu rats (Hllron, 1965,, Slrian and Chtnesc has ndt prcviou\ly been poss~ble tsith lnfntionr by hiln~stcr.I;B inforJ. 1965: Waters & Nivcn. 1965.1 .. .rnJ $mall nunihcrs of h:~cill(~r crolow, vdxinarion. rtua species of Myshonlys (Binford, 1968). These other species have not been employed extensively in lahoratory experiments, probably because the mouse is the most convenient and readily available laboratory animal and because in some of the species mentioned early bacillary growth (within the first 6 months or so) is less extensive than in the mouse.

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