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World Health Organization : Organisation Mondiale de la Sante ; Serie de Monographies, Volume Number 43 - (Chapter 4): Chapter 4 Problems in Immunology

By World Health Organization

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Book Id: WPLBN0000041315
Format Type: PDF eBook
File Size: 9.4 MB
Reproduction Date: 2005
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Title: World Health Organization : Organisation Mondiale de la Sante ; Serie de Monographies, Volume Number 43 - (Chapter 4): Chapter 4 Problems in Immunology  
Author: World Health Organization
Volume:
Language: English
Subject: Health., Public health, Wellness programs
Collections: Medical Library Collection, World Health Collection
Historic
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Publisher: World Health Organization

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Organization, W. H. (n.d.). World Health Organization : Organisation Mondiale de la Sante ; Serie de Monographies, Volume Number 43 - (Chapter 4). Retrieved from http://hawaiilibrary.net/


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Medical Reference Publication

Excerpt
Toxin Production Dealing with the cholera problem at a conference held in 1884 at Berlin Koch considered this disease essentially as a toxicosis, caused by a poison which the causative organisms excreted. However, the experimental evidence soon procured b). some workers was not in favour of the presence of such an exotoxin. Thus Nicati & Rietsch (1884), the pioneers in this field, found the filtrates of young broth cultures of Vibrio cholerae incapable of producing signs of toxicosis in dog. However, an intoxication, characterized by vomiting, dyspnoea or general depression, and paralysis of the extremities, could be produced in dogs injected intravenously with the filtrates of cholera cultures a week or more old, and led in some of the animals to death within 12 hours.

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