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Controlled Clinical Studies of Air Pollutant Exposure : Evaluating Scientific Information in Relation to Air Quality Standards

By Hackney, Jack D.

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Book Id: WPLBN0000064252
Format Type: PDF eBook
File Size: 0.4 MB
Reproduction Date: 2005

Title: Controlled Clinical Studies of Air Pollutant Exposure : Evaluating Scientific Information in Relation to Air Quality Standards  
Author: Hackney, Jack D.
Volume:
Language: English
Subject: Government publications, United Nations., United Nations. Office for Disarmament Affairs
Collections: Government Library Collection, Disarmament Documents
Historic
Publication Date:
Publisher: United Nations- Office for Disarmament Affairs (Unoda)

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Hackney, J. D. (n.d.). Controlled Clinical Studies of Air Pollutant Exposure : Evaluating Scientific Information in Relation to Air Quality Standards. Retrieved from http://hawaiilibrary.net/


Description
Government Reference Publication

Excerpt
Introduction: This paper focuses on clinical studies of human volunteers deliberately exposed to specific air pollutants. Most such investigations are performed for the express purpose of guiding air quality regulatory decisions. They establish atmospheric conditions in a controlled laboratory setting which are considered relevant to actual ambient polluted atmospheres and attempt to document any health-related effects which result from breathing the laboratory atmospheres. Clinical studies to some extent combine the strong point of animal toxicology-rigorous control of the experimental subject and environment- with the strong point of epidemiologyunquestioned relevance to human health. However, clinical studies are limited by ethical and practical considerations to small groups of people, short durations of exposure, and atmospheres expected to produce only mild and temporary health effects, at most. Regulatory agencies must consider large and diverse populations at risk of long-term as well as short-term effects, and must try to protect the most susceptible.

 

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