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Bulletin of the World Health Organization : 2004; Volume 82, Number 3, Year 2004 82 (3), Pages 162: Gender and the 10/90 Gap in Health Research

By Lesley Doyal

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Book Id: WPLBN0000181419
Format Type: PDF eBook
File Size: 0.1 MB
Reproduction Date: 2005

Title: Bulletin of the World Health Organization : 2004; Volume 82, Number 3, Year 2004 82 (3), Pages 162: Gender and the 10/90 Gap in Health Research  
Author: Lesley Doyal
Volume:
Language: English
Subject: Health., Public health, Wellness programs
Collections: Medical Library Collection, World Health Collection
Historic
Publication Date:
Publisher: World Health Organization

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Doyal, L. (n.d.). Bulletin of the World Health Organization : 2004; Volume 82, Number 3, Year 2004 82 (3), Pages 162. Retrieved from http://hawaiilibrary.net/


Description
Medical Reference Publication

Excerpt
International standards for diphtheria toxoid, plain, and for tetanus toxoid were established in 1951.6 Both preparations are relatively highly purified toxoids. Preparations of this nature have, however, proved somewhat of a disadvantage in assay work so far as diphtheria toxoid is concerned. It has been generally observed that the slopes of dosage-response lines for fluid diphtheria toxoids tend to become flatter as the purity increases; adsorbed preparations generally have steeper slopes than crude fluid preparations. Because of this the usefulness of the plain diphtheria toxoid standard is somewhat limited as a working standard, and a further standard for adsorbed preparations has been propo~ed.~I t has been claimed, however, by the WHO Expert Committee on Biological Standardization, that the slopes of dosage-response lines for plain and adsorbed preparations of tetanus toxoids are closely similar, and thus a single standard was considered ~atisfactory.~T he latter opinion requires some qualification in the light of certain results obtained in the Laboratory of Hygiene and recorded here.

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