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Dna Computing

By Lewis, N.

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Book Id: WPLBN0000184738
Format Type: PDF eBook
File Size: 1.1 MB
Reproduction Date: 2008
Full Text

Title: Dna Computing  
Author: Lewis, N.
Volume:
Language: English
Subject: Government publications, Legislation., Government Printing Office (U.S.)
Collections: Government Library Collection
Historic
Publication Date:
Publisher: Government Printing Office

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Lewis, N. S. (n.d.). Dna Computing. Retrieved from http://hawaiilibrary.net/


Excerpt
Excerpt: The field of DNA computing has sprung from nowhere to become a fashionable and exciting area. The hope of the field is that the pattern matching and polymerization processes of DNA chemistry, combined with the enormous number of molecules in a pound, will make feasible computations that are now too hard for conventional computers.

Table of Contents
Contents 1 DNA COMPUTING 1 1.1 The Hope . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 1.2 The Basic Approach . . . . . . . . . . . . . . . . . . . . . . . 1 1.3 Encoding a Problem onto a DNA Strand . . . . . . . . . . . . 2 1.4 Basic Computational Operations on a DNA Strand . . . . . . 2 1.5 An Example: Breaking 56 Bit DES Using DNA . . . . . . . . 4 1.5.1 Constructing All Bit Strings . . . . . . . . . . . . . . . 4 1.5.2 Typical Computation on DNA . . . . . . . . . . . . 5 1.6 How Much is a Mole? . . . . . . . . . . . . . . . . . . . . . . . 6 1.7 Is There a Niche for DNA Computing? . . . . . . . . . . . . . 8 1.8 A Useful Research Program . . . . . . . . . . . . . . . . . . . 11 1.9 Algorithms and Theory . . . . . . . . . . . . . . . . . . . . . . 11 1.10 Experiment and Engineering . . . . . . . . . . . . . . . . . . . 11 1.10.1 PCR . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 1.10.2 Extracting . . . . . . . . . . . . . . . . . . . . . . . . . 13 1.10.3 Cutting and Reconnecting DNA . . . . . . . . . . . . . 14 1.10.4 Very Large Scale Production of Restriction Enzymes, Ligases and Affinity Columns . . . . . . . . . . . . . . 14 1.10.5 Controlling the Yieldof DesiredLength DNA Strings . 14 1 . 11 Circumventing the Restriction of a Mole of DNA . . . . . . . . 15 1.11 .1 A Cost Comparison . . . . . . . . . . . . . . . . . . . . 16 1.11.2 Nucleotides (i.e., Raw Materials) . . . . . . . . . . . . 16 1.11.3 Ligases . . . . . . . . . . . . . . . . . . . . . . . . . . . 17 1.11 .4 Restriction Enzymes . . . . . . . . . . . . . . . . . . . 20 1.11 .5 Hybridization Enzymes . . . . . . . . . . . . . . . . . . 21 1.11.6 Polymerase . . . . . . . . . . . . . . . . . . . . . . . . 22 1.11 .7 Cost Summary and Comparison . . . . . . . . . . . . . 22 1.12 Summary and Conclusions . . . . . . . . . . . . . . . . . . . . 23

 

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