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World Health Organization : Regioinal Office for Africa ; Year 1993 ; Africa Region, Education and Training, Issue 149: Meeting of the Executive Committee of the African Council for the Training and Promotion of Health Sciences Teachers and Specialists

By World Health Organization

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Book Id: WPLBN0000186824
Format Type: PDF eBook
File Size: 0.6 MB
Reproduction Date: 2005

Title: World Health Organization : Regioinal Office for Africa ; Year 1993 ; Africa Region, Education and Training, Issue 149: Meeting of the Executive Committee of the African Council for the Training and Promotion of Health Sciences Teachers and Specialists  
Author: World Health Organization
Volume:
Language: English
Subject: Health., Public health, Wellness programs
Collections: Medical Library Collection, World Health Collection
Historic
Publication Date:
Publisher: World Health Organization

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Organization, W. H. (n.d.). World Health Organization : Regioinal Office for Africa ; Year 1993 ; Africa Region, Education and Training, Issue 149. Retrieved from http://hawaiilibrary.net/


Description
Medical Reference Publication

Excerpt
The need to investigate further the phenomenon of sulfone-induced haemolysis is becoming greater as the use of sulfones may increase, particularly for malaria therapy in areas where Plasmodium falciparum is found to be resistant to chloroquine. The authors report on studies of the haemolytic efects of diaphenylsulfone (DDS) administered orally, in-doses ranging from 25 rng to 300 mg daily for 21 days, to normal healthy men and to healthy Negro men with deficiency of glucose-6-phosphate dehydrogenase (G-6-PD) . The latter proved more susceptible to diaphenylsulfone-induced haemolysis than did normal men. There was a direct relationship between the dose of diaphenylsuIfone and the extent of haemolysis in both groups of men studied.

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