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Plos One : the Deinococcus Radiodurans Dr1245 Protein, a Ddrb Partner Homologous to Ybjn Proteins and Reminiscent of Type III Secretion System Chaperones, Volume 7

By Dmitriev, Oleg, Y.

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Book Id: WPLBN0003960886
Format Type: PDF eBook :
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Reproduction Date: 2015

Title: Plos One : the Deinococcus Radiodurans Dr1245 Protein, a Ddrb Partner Homologous to Ybjn Proteins and Reminiscent of Type III Secretion System Chaperones, Volume 7  
Author: Dmitriev, Oleg, Y.
Volume: Volume 7
Language: English
Subject: Journals, Science, Medical Science
Collections: Periodicals: Journal and Magazine Collection
Historic
Publication Date:
Publisher: Plos

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Dmitriev, O. Y. (n.d.). Plos One : the Deinococcus Radiodurans Dr1245 Protein, a Ddrb Partner Homologous to Ybjn Proteins and Reminiscent of Type III Secretion System Chaperones, Volume 7. Retrieved from http://hawaiilibrary.net/


Description
Description : The bacterium Deinococcus radiodurans exhibits an extreme resistance to ionizing radiation. A small subset of Deinococcus genus-specific genes were shown to be up-regulated upon exposure to ionizing radiation and to play a role in genome reconstitution. These genes include an SSB-like protein called DdrB. Here, we identified a novel protein encoded by the dr1245 gene as an interacting partner of DdrB. A strain devoid of the DR1245 protein is impaired in growth, exhibiting a generation time approximately threefold that of the wild type strain while radioresistance is not affected. We determined the three-dimensional structure of DR1245, revealing a relationship with type III secretion system chaperones and YbjN family proteins. Thus, DR1245 may display some chaperone activity towards DdrB and possibly other substrates.

 

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